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Williams College Biologist Lara Hutson Wins $220,000 NIH Grant

01:51PM / Wednesday, July 02, 2008
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WILLIAMSTOWN - The National Institutes of Health (NIH) has awarded a two-year grant of $220,076 to Williams College Assistant Professor of Biology Lara D. Hutson, in support of her research on Charcot-Marie-Tooth disease or CMT.

CMT is the most common inherited neuromuscular disease, affecting as many as one in every 2,500 individuals. CMT usually shows dominant inheritance and symptoms generally appear during adolescence or young adulthood. It is characterized by degeneration of long motor and sensory axons, which results in muscle atrophy and skeletal deformities.

Hutson's research will use zebrafish as a model system to investigate disease mutations in two small heat shock proteins, HSP27 and HSPB8, which can cause either CMT or the closely related disease Distal Hereditary Motor Neuropathy (dHMN). The results of these studies will help to better understand the cell biological events leading to axon degeneration in CMT and dHMN.

Since these diseases are likely determined, at least in part, by environmental factors, the results of these studies could have implications for the prevention and management of these diseases.

Hutson received her B.A. from the University of California at San Diego and her Ph.D. from the University of Washington. She did her postdoctoral work in neurobiology and anatomy at the University of Utah.
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I am beyond thrilled to hear about this wonderful news. It is so encouraging to hear about monies that are being allocated towards finding a cure for this highly mis-diagnosed disease.
from: Mark Boxshuson: 07-10-2008
I am thrilled to hear about this. As a person living with CMT, this gives me alot of hope that the disease will one day be arrested. I'm also pleased to see another university and professor doing CMT research. I belong to cmtushope.info where we follow CMT research.
from: Bevon: 07-02-2008
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